Cantargia AB: Cantargia submits application to start new

cantargia: can04 har bredare angreppssätt än - Aktiellt

It is developing CAN04 and CAN10 against IL1RAP. CAN04 is in a Phase IIa clinical trial, CANFOUR, in solid tumours focused on NSCLC and PDAC. It is preparing to file an IND and initiate a trial in the US next year. 2019-7-5 · Cantargia's antibody CAN04 (nidanilimab) is being investigated in an open label three-armed phase IIa clinical trial, CANFOUR. CAN04 will be examined as monotherapy or in chemotherapy combinations in patients with NSCLC or PDAC. The study is designed for 20 patients in monotherapy and approximately 30 patients in each combination arm.

CAN04, an antibody targeting interleukin 1 receptor accessory protein (IL1RAP), is currently being investigated for treatment of non-small cell lung cancer (NSCLC) and pancreatic cancer (PDAC) in phase IIa clinical development in Europe. 2020-4-7 · Cantargia Submits IND Application for CAN04 PR Newswire STOCKHOLM, April 7, 2020 STOCKHOLM, April 7, 2020 /PRNewswire/ -- Cantargia AB today announced that the application for a US IND regarding Cantargia is now in the process of broadening the development activities and the next step is a phase Ib trial investigating CAN04 in combination with the PD1 binding antibody pembrolizumab 2020-10-2 · Cantargia develops antibody-based pharmaceuticals against interleukin-1 receptor accessory protein (IL1RAP). The antibody CAN04 binds IL1RAP with high affinity and functions through both 2021-2-26 · Cantargia AB today announced that the IND application regarding the antibody CAN04 has been approved by the US FDA. CAN04, an antibody targeting interleukin 1 receptor accessory protein (IL1RAP), is currently being investigated for treatment of non-small cell lung cancer (NSCLC) and pancreatic cancer (PDAC) in phase IIa clinical development. 2021-3-19 · Cantargia develops antibody-based pharmaceuticals against interleukin-1 receptor accessory protein (IL1RAP). The lead project CAN04 is in phase IIa clinical development for treatment of cancer Detailed Description: CAN04 is a first-in-class fully humanized and ADCC enhanced monoclonal antibody, targeting the Interleukin 1 Receptor Accessory Protein (IL1RAP). The CAN04 strategy is to attack the IL1RAP target molecule using an effective antibody-based cancer treatment. 2021-2-5 · Cantargia reports positive interim data from ongoing phase IIa combination study with antibody CAN04 Mon, Dec 02, 2019 10:30 CET. Cantargia AB today announced the first interim data with antibody CAN04 in combination with chemotherapy in the ongoing phase IIa CANFOUR study.

Cantargia ansöker om ny klinisk studie för CAN04

Det mest intressanta i presentation var att få se nivåsänkningarna av IL-6 och CRP, vilket är relevant då dessa biomarkörer visats korrelera med patientöverlevnad.. Antikroppen CAN04 binder starkt till målmolekylen IL1RAP och fungerar genom både ADCC och blockering av IL-1α- och IL-1β-signalering. CAN04 kan därmed motverka IL-1-systemets bidrag till en immunsuppressiv mikromiljö i tumörer liksom utvecklandet av resistens mot cellgiftsbehandling.

CANTA, Cantargia, SE0006371126 - Nasdaq

The CAN04 strategy is to attack the IL1RAP target molecule using an effective antibody-based cancer treatment. 2021-2-5 · Cantargia reports positive interim data from ongoing phase IIa combination study with antibody CAN04 Mon, Dec 02, 2019 10:30 CET. Cantargia AB today announced the first interim data with antibody CAN04 in combination with chemotherapy in the ongoing phase IIa CANFOUR study. Cantargia AB today announced the submission of a clinical trial application investigating antibody CAN04 in combination with FOLFIRINOX for first line treatment of metastatic pancreatic cancer 2020-5-14 · Cantargia is a Swedish biotechnology company focused on developing new concepts for immunotherapeutic treatment of cancer and autoimmune / inflammatory diseases. Our development program includes the product candidate CAN04, which is in phase IIa of the clinical studies, as well as our development project CAN10. 2021-3-1 · Cantargia AB (publ), reg. no.

Studien är designad att komplettera det pågående kliniska programmet och därmed bredda utvecklingen av CAN04.
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The lead project CAN04 is in phase IIa clinical development for treatment of cancer Detailed Description: CAN04 is a first-in-class fully humanized and ADCC enhanced monoclonal antibody, targeting the Interleukin 1 Receptor Accessory Protein (IL1RAP). The CAN04 strategy is to attack the IL1RAP target molecule using an effective antibody-based cancer treatment. 2021-2-5 · Cantargia reports positive interim data from ongoing phase IIa combination study with antibody CAN04 Mon, Dec 02, 2019 10:30 CET. Cantargia AB today announced the first interim data with antibody CAN04 in combination with chemotherapy in the ongoing phase IIa CANFOUR study. Cantargia AB today announced the submission of a clinical trial application investigating antibody CAN04 in combination with FOLFIRINOX for first line treatment of metastatic pancreatic cancer 2020-5-14 · Cantargia is a Swedish biotechnology company focused on developing new concepts for immunotherapeutic treatment of cancer and autoimmune / inflammatory diseases.

For further information, please contact Göran Forsberg, CEO 2019-8-26 · Cantargia AB (STO:CANTA)), a biotechnology company that develops antibody-based treatments for life-threatening diseases, announced on Friday the signing of an extension of its agreement with BioWa Inc around the BioWa proprietary POTELLIGENT Technology for production of Cantargia's antibody drug candidate CAN04. Cantargia ansöker om start av ny klinisk studie kring antikroppen CAN04 och FOLFIRINOX i bukspottkörtelcancer. Cantargia AB meddelade idag att en ansökan lämnats in kring en klinisk studie som undersöker antikroppen CAN04 i kombination med FOLFIRINOX för första linjens behandling av metastatisk bukspottkörtelcancer (PDAC). Cantargia AB today announced that the application for a US IND regarding the antibody CAN04 has been submitted to the US FDA. CAN04, an antibody targeting interleukin 1 receptor accessory protein (IL1RAP), is currently being investigated for treatment of non-small cell lung cancer (NSCLC) and pancreatic cancer (PDAC) in phase IIa clinical development in Europe.
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cantargia: can04 har bredare angreppssätt än - Aktiellt

It is developing two assets against IL1RAP, CAN04 and CAN10. The lead clinical trial is a Phase IIa CANFOUR study with CAN04 in non-small cell lung cancer and pancreatic cancer. "Cantargia’s decision to increase the level of ambition in the CAN04 project is among the most important and the most intensified in the company's history. This marks a major step to enhance the value of the CAN04 project and take greater advantage of the potential around the target IL1RAP (Interleukin 1 Receptor Associated Protein). This study will consider the safety and effectiveness of a study drug, CAN04, in combination with pembrolizumab, in the treatment of incurable or metastatic non-small-cell lung cancer, head and neck squamous cell carcinoma, urothelial cancer, or malignant melanoma.

Cantargia AB: Cantargia reports first patient treated with

Unlike other intelligence solutions, BCIQ exclusively supports the unique needs of the biopharma industry and 2021-4-11 · Can04, like canakinumab, is also being tested in combination with Keytruda. Its 2026 sales forecasts sit at $564m, according to EvaluatePharma ’s sellside consensus. Cantargia’s investors have been spooked by the cana readout; the company’s shares are down 23% so far today. · Both parts of the IL-1 system are upregulated in tumor tissue after chemotherapy · CAN04, blocking the activity of both forms of IL-1, increases the efficacy of several different | January 10, 2021 STOCKHOLM, March 1, 2021 /PRNewswire/ -- Cantargia AB ("Cantargia") will participate at several international investor conferences during March to present the company, the drug candidates CAN04 and CAN10 and future plans.

2 days ago · More information about Cantargia is available at www.cantargia.com. About CAN04 The antibody CAN04 binds strongly to the target IL1RAP and functions both though ADCC as … Cantargia AB (“Cantargia”) today announces that the first patient in the CANFOUR clinical trial has received three cycles of treatment with the antibody CAN04. Thereby, the first patient has formally completed the safety evaluation period according to the clinical protocol. Two additional patients have received therapy with CAN04. About Cantargia Cantargia AB (publ), reg.